Indicative Scientific Publications
Evidence-based insights advancing cardiometabolic health
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Testosterone Replacement Therapy (TRT)
Testosterone replacement therapy (TRT) offers a game-changing solution for men experiencing age-related declines in testosterone, accompanied by symptoms like fatigue, increase in body fat, abdominal obesity, reduced muscle mass (sarcopenia), reduced bone density (osteopenia/osteoporosis), low libido, erectile dysfunction and depressive mood.
TRT not only restores energy and vitality but also aids in building muscle, burning fat, and improving bone health.
For men struggling with weight loss or metabolic conditions like type 2 diabetes, TRT can enhance insulin sensitivity and promote better body composition.
If you’re noticing these symptoms, consider consulting a specialist to check your testosterone levels and discuss if TRT is right for you.
When combined with exercise, a healthy diet, and regular medical monitoring, TRT can be a safe and effective way to regain control of your health and fitness.
Hormones (Athens). 2024 Dec;23(4):801-817.
DOI: 10.1007/s42000-024-00587-2
Keywords:
- Aging
- Benefits
- Functional hypogonadism
- Late-onset hypogonadism
- Safety
- Testosterone therapy
- Publication source: PubMed
Growth Hormone Therapy in Heart Failure
Living with chronic heart failure often means reduced energy, limited exercise capacity, and a diminished quality of life. However, according to our recent meta-analysis, growth hormone (GH) therapy offers hope.
GH can improve heart function, increase oxygen use during exercise, help patients feel more energized, and decrease the risk of hospitalization or death. This means you could walk farther, climb stairs more easily, and enjoy activities you once struggled with.
For people with ischemic heart failure, GH has shown even greater potential.
While still under study, GH therapy could become a valuable addition to traditional heart failure treatments, especially for those seeking to improve physical activity and overall well-being.
J Clin Endocrinol Metab. 2024 Nov 21:dgae814.
DOI: 10.1210/clinem/dgae814
Keywords:
- Anabolic Hormones
- Growth Hormone Therapy
- Heart Failure
- Insulin-Like Growth Factor-1
- Meta-analysis
- Multiple Hormonal Deficiency Syndrome
- Publication source: PubMed

Personalized Anti-Aging Interventions
Aging is not just about the increase in chronological age but is influenced by complex biological changes that vary from person to person.
According to our recent publication, the integration of artificial intelligence with advanced multi-omics technologies (genomics, epigenomics, proteomics, metabolomics, microbiomics) allows scientists to decode the aging process and develop personalized anti-aging strategies.
Imagine a future where a simple blood test can reveal your unique biological aging markers and recommend specific lifestyle adjustments, supplements, or therapies to slow down the aging process.
This publication promotes the implementation of scientifically proven interventions, such as healthy diets, exercise, and targeted supplements, tailored to each individual's needs to prevent aging-related diseases and promote active and healthy aging.
J Pers Med. 2024 Aug 31;14(9):931.
DOI: 10.3390/jpm14090931
Keywords:
- Aging research
- Geroscience
- Hallmarks of aging
- Machine learning
- Multi-omics technologies
- Personalized medicine
- Publication source: PubMed

Beyond Calories: Why Weight Management Requires a Personalized Approach
Weight loss isn’t as simple as eating fewer calories—it’s about understanding how your unique metabolism and hormones respond to diet and exercise.
For example, some people may burn fat more efficiently during low-intensity exercise, while others thrive on slightly higher-intensity workouts.
Similarly, your body type, genetics, and hormonal balance affect how your body stores or loses fat and muscle following a nutritional intervention.
This research encourages people to move beyond one-size-fits-all diets and adopt personalized strategies like Precision Medicine, where meal plans and exercise routines are tailored to their specific needs.
By working with a professional to analyze your metabolic profile, you can create a plan that’s more effective, sustainable, and suited to your body’s unique rhythms.
Keywords:
- Body composition
- Metabolic health
- Nutrition
- Personalized medicine
- Precision Medicine
- Weight management

Lifestyle Medicine Interventions Inspired by Blue Zones for Longevity and Vitality
Inspired by Blue Zones: Areas like Okinawa, Sardinia, and Ikaria, renowned for their extreme longevity, show that simple, evidence-based lifestyle habits can significantly enhance life expectancy and healthspan. This paper provides practical ways to integrate these principles into daily life.
Mediterranean-Inspired Eating: Embrace a diet rich in vegetables, legumes, nuts, whole grains, and olive oil, while limiting processed foods and sugars. Follow the 80% rule—stop eating when you're 80% full—to avoid overeating.
Move Naturally: Incorporate low-intensity, everyday activities like walking, gardening, or household chores.
Social Connections: Foster strong relationships and prioritize time with family and friends, as meaningful connections are linked to reduced stress and better health.
Purposeful Living: Discover your "why"—a clear sense of purpose that inspires your daily life—linked to greater longevity and life satisfaction.
Stress Management: Practice simple daily rituals like mindfulness, prayer, or yoga to reduce stress and improve mental well-being.
Am J Lifestyle Med . 2022 Aug 20;18(6):750-765.
DOI: 10.1177/15598276221118494.
Keywords:
- Blue Zones
- Genetics
- Lifestyle medicine
- Longevity
- Wellbeing
- Publication source: PubMed
Research Impact
Our research directly informs our clinical practice, ensuring that our treatments are based on the latest scientific evidence. This integration of research and practice allows us to offer cutting-edge solutions while maintaining the highest standards of safety and efficacy.